Private _doc As New XmlDocument
_doc.ChildNodes(1).ChildNodes(0).InnerText = TextBox1.Text
_doc.ChildNodes(1).ChildNodes(1).InnerText = TextBox2.Text
_doc.ChildNodes(1).ChildNodes(2).InnerText = TextBox3.Text
_doc.Save(Application.StartupPath & "\test.xml")