Showing error while sending mail on PROD environment running fine in local

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Hi All,
I am not able to send mail from PROD environmet, working fine in local system.
Showing below error message:
System.Net.WebException: Unable to connect to the remote server ---> System.Net.Sockets.SocketException: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond 10.25.3.206:25
at System.Net.Sockets.Socket.DoConnect(EndPoint endPointSnapshot, SocketAddress socketAddress)
at System.Net.ServicePoint.ConnectSocketInternal(Boolean connectFailure, Socket s4, Socket s6, Socket& socket, IPAddress& address, ConnectSocketState state, IAsyncResult asyncResult, Int32 timeout, Exception& exception)
--- End of inner exception stack trace ---
at System.Net.ServicePoint.GetConnection(PooledStream PooledStream, Object owner, Boolean async, IPAddress& address, Socket& abortSocket, Socket& abortSocket6, Int32 timeout)
at System.Net.PooledStream.Activate(Object owningObject, Boolean async, Int32 timeout, GeneralAsyncDelegate asyncCallback)
at System.Net.PooledStream.Activate(Object owningObject, GeneralAsyncDelegate asyncCallback)
at System.Net.ConnectionPool.GetConnection(Object owningObject, GeneralAsyncDelegate asyncCallback, Int32 creationTimeout)
at System.Net.Mail.SmtpConnection.GetConnection(ServicePoint servicePoint)
at System.Net.Mail.SmtpTransport.GetConnection(ServicePoint servicePoint)
at System.Net.Mail.SmtpClient.GetConnection()
at System.Net.Mail.SmtpClient.Send(MailMessage message)
Please help ..
Thanks in advance.

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